Real Madrid slumped to a 2-1 defeat at Real Betis after their former player Isco converted a second-half penalty on Saturday, denying the visitors the chance to top LaLiga.
The loss leaves Real Madrid level on 54 points with leaders Barcelona, who host mid-table Real Sociedad on Sunday.
Third-placed Atletico Madrid, who have 53, could go top later on Saturday when they host fourth-placed Athletic Bilbao.
